佟晓永教授
心血管药理研究室
邮箱: xiaoyongtong@cqu.edu.cn
个人简历
1990年9月-1995年6月 哈尔滨医科大学, 医学学士
1995年9月-1998年7月 哈尔滨医科大学, 医学硕士 (导师:李蓉教授)
1998年9月-2001年7月 中国协和医科大学, 药理学博士(导师:王晓良研究员)
2001年12月-2002年10月 美国乔治城大学,助理研究员(导师:Dr. Martin Morad)
2002年10月-2005年9月 美国纽约大学,助理研究员(导师:Dr. William A. Coetzee)
2005年10月-2007年8月 美国波士顿大学 博士后(导师:Dr. Richard A. Cohen)
2007年9月-2014年9 月美国波士顿大学 助理教授
2014年9月-至今 中国重庆大学 教授
研究领域
动脉粥样硬化硬化,血管损伤后再狭窄,血管再生,腹主动脉瘤,高血压
科研经费
1.中国重庆大学“百人计划”启动基金,2014/09-2017/09,编号:0236011104413
2.中央高校基本科研业务费,2015年1月-2017年1月,编号:0236015202008
3.国家自然基金面上项目,2016年1月-2019年12月,编号:31571172
近几年被SCI引用的通讯作者文章
1. Tong XY*, Hou X, Jourd’heuil D, Weisbrod RM, Cohen RA (2010). Upregulation of Nox4 by TGF beta1 oxidizes SERCA and inhibits NO in arterial smooth muscle of the prediabetic Zucker rat. Cir Res.107 (8):975-83. PMID: 20724704
2. Tong XY*, Evangelista A, Cohen RA (2010). Targeting the redox regulation of SERCA in vascular physiology and disease. Curr Opin Pharmacol. 10(2):133-8. PMID: 20045379
3. Cohen RA and Tong XY*. (2010). Vascular oxidative stress: the common link in hypertensive and diabetic vascular disease. J Cardiovascu Pharmacol. 55(4):308-16. PMID: 20422735
4. Mei Y, Thompson MD, Cohen RA, Tong X* (2013). Endoplasmic reticulum stress and related pathological processes. J Pharmacol Biomed Anal. 1(2): 1000107. PMID: 24611136
5. Qin ZX, Hou XY, Weisbrod RM, Cohen RA, Tong X* (2014). Nox2 mediates high fat high sucrose diet induced nitric oxide dysfunction and inflammation in smooth muscle cells. J Mol Cell Cardiol. 72:56-63. PMID: 24631774
6. Thompson MD, Mei Y, Weisbrod RM, Silver M, Shukla PC, Silver M, Bolotina VM, Cohen RA*, Tong X*(2014). Glutathione adducts on sarcoplasmic/endoplasmic reticulum Ca2+ ATPase C674 regulate endothelial cell calcium stores and angiogenic function as well as promote ischemic blood flow recovery. J Biol Chem. 289(29):19907-16. PMID: 24920669
7. Mei Y, Thompson MD, Shiraishi Y, Cohen RA*, Tong X*(2014). Sarcoplasmic/endoplasmic reticulum Ca2 + ATPase C674 promotes ischemia- and hypoxia-induced angiogenesis via coordinated endothelial cell and macrophage function. J Mol Cell Cardiol. 76: 275-282. PMID: 25260714
8. Chen LL, Hou XY, Xiao J, Thompson MD, Kuroda J, Ago T, Sadoshima J, Tong XY*(2014). Both hydrogen peroxide and transforming growth factor beta 1 contribute to endothelial Nox4 mediated angiogenesis. BBA Molecular Basis of Disease. 1842(12):2489-2499. PMID: 25315297
9. Mei Y, Thompson MD, Cohen RA, Tong X*(2015). Autophagy and protein quality control in cardiometabolic diseases. BBA Molecular Basis of Disease. 1852(2):243-251. PMID: 24834848
10. Tong X*, Khandelwal AR, Qin Z, Wu X, Chen L, Ago T, Sadoshima J, Cohen RA(2015). Role of smooth muscle Nox4-based NADPH oxidase in neointimal hyperplasia. J Mol Cell Cardiol. 89:185-194. PMID: 26582463
11. Tong X*, Khandelwal AR, Wu X, Xu Z, Yu W, Chen C, Zhao W, Yang J, Qin Z, Weisbrod RM, Seta F, Ago T, Lee KS, Hammock BD, Sadoshima J, Cohen RA, Zeng C (2016). Pro-atherogenic role of smooth muscle Nox4-based NADPH oxidase. J Mol Cell Cardiol. 92:30-40. PMID: 26812119
12.Hu P, Wu X, Khandelwal AR, Yu W, Xu Z, Chen L, Yang J, Weisbrod RM, Lee KS, Seta F, Hammock BD, Cohen RA, Zeng C, Tong X* (2017). Endothelial Nox4-based NADPH oxidase regulates atherosclerosis via soluble epoxide hydrolase. BBA Molecular Basis of Disease. 1836(6):1382-1391.
13.Tong X*, Hou X, Wason C, Kopel T, Cohen RA, Dember LD* (2017). Smooth muscle nitric oxide responsiveness and clinical maturation of hemodialysis arteriovenous fistulae. American Journal of Pathology. (accepted)