王震职称:副教授 学历:博士 邮箱:wangz1114@cqu.edu.cn 电话: |
2015年11月-至今:重庆大学药学院(创新药物研究中心),专任教师/副教授;
2014年8月-2015年11月:新加坡国立大学,博士后,导师:Prof. Lu Yixin;
2009年9月-2014年7月:四川大学化学学院,理学博士,导师:冯小明院士;
2005年9月-2009年6月:四川大学化学学院,理学学士,导师:冯小明院士。
不对称合成方法学(有机催化/手性路易斯酸催化)
药物化学,生物活性化合物的合成研究
不对称催化是化学学科以及药物化学领域的前沿和研究热点,是获得光学活性化合物最高效的途径。王震博士长期从事有机合成和不对称催化工作,在手性金属配合物催化(主要是镧系路易斯酸金属催化,博士期间)以及有机小分子催化(手性氨基酸衍生的有机膦催化,博士后期间)等方面进行了系统的研究,取得了系列开拓性的创新成果。王震博士已在J. Am. Chem. Soc.,Angew.Chem. Int. Ed.,Chem. Commun.,Org. Lett.等国际权威刊物上发表论文多篇。
一、编写书籍、章节
(2) Xiaoming Feng*, Zhen Wang, Xiaohua Liu, Chiral Lewis Acid, “Chiral Lewis Acid Rare-Earth Metal Complexes in Enantioselective Catalysis”, Springer International Publishing AG, 2017, 147-192, DOI: 10.1007/3418_2017_1.
(1) Xiaoming Feng, Zhen Wang, Lili Lin, Electronic Encyclopedia of Reagents for Organic Synthesis, “1,3-Dicyclohexylcarbodiimide”, Wiley, 2017, 5-9.
二、论文发表
(25) Zhen Wang, Xiaohua Liu*, Xiaoming Feng*, “Asymmetric Catalysis Enabled by Chiral N,N'-Dioxide–Nickel(II) Complexes”, Aldrichimica Acta 2020, 53, 3.
(24) Xin Wang, Mengxue Lu, Qin Su, Minghui Zhou, Yesu Addepalli, Weijun Yao, Zhen Wang* and Yixin Lu*,“Phosphine-catalyzed [4+2] cycloadditions of allenic ketones: Enantioselective synthesis of functionalized tetrahydropyridines”, Chem. Asian J. 2019, 14, 3409-3413.
(23) Zhen Wang*, Yesu Addepalli, and Yun He*, “Construction of Polycyclic Indole Derivatives via Multiple Aryne Reactions with Azaheptafulvenes”, Org. Lett. 2018, 20, 644.
(22) Yesu Addepalli, Xiaohong Yang, Minghui Zhou, D. Prabhakar Reddy, Shao-Lin Zhang, Zhen Wang* and Yun He*, “Synthesis and anticancer activity evaluation of novel azacalix[2]arene[2]pyrimidines”, Eur. J. Med. Chem. 2018, 151, 214.
(21) Minghui Zhou, Qin Su, Yesu Addepalli, Yun He* and Zhen Wang*, “An asymmetric Mannich reaction of α-diazocarbonyl compounds and N-sulfonyl cyclic ketimines catalyzed by complexes generated from chiral and achiral phosphines with gold(I)”, Org. Biomol. Chem. 2018, 16, 2923.
(20) Yesu Addepalli, Zhimei Yu, Jie Ji, Cheng Zou, Zhen Wang* and Yun He*, “Tandem Diels–Alder/oxidation–aromatization reactions involving 2-styrylchromones and arynes”, Org. Biomol. Chem. 2018, 16, 6077.
(19) Prabhakar Reddy, Ning Zhang, Zhimei Yu, Zhen Wang, Yun He*, “Total Synthesis of Kanamienamide”. J. Org. Chem., 2017, 82, 11262.
(18) Zhen Wang,* Tianli Wang, Weijun Yao and Yixin Lu* “Phosphine-Catalyzed Enantioselective [4 + 2] Annulation of o-Qu...