Hailong Yan

https://www.x-mol.com/groups/yan_hailong

Asymmetric synthesis of drug and natural products

Awards

1.  National Outstanding Youth Foundation (2019)

2.  Asian Core Program Lectureship Award (Singapore and Korea 2018)

3.  National Ten Thousand People Plan (2018)

Grants and fundings

1.  National Outstanding Youth Foundation

2.  National Ten Thousand People Plan

3.  National Natural Science Foundation of China

4.  Special Key Research and Development Projects of Common Key Technology Innovation for Key Industries in Chongqing

5.  Chongqing Natural Science Foundation

1.  Huang, S.; Wen, H.; Tian, Y; Wang, P.; Qin, W.; Yan, H*. Organocatalytic Enantioselective Construction of Chiral Azepine Skeleton Bearing Multiple-Stereogenic Elements. Angew. Chem. Int. Ed. 2021, 60, 2-10.

2.  Liu, Y.; Liu, S.; Li, D.; Zhang, N.; Peng, L.; Ao, J.; Song, C. E.; Lan, Y.; Yan, H*. Kinetic Resolution of Allylic Alcohol with Chiral BINOL-Based Alkoxides: A Combination of Experimental and Theoretical Studies. J. Am. Chem. Soc. 2019, 141, 1150-1159.

3.  Jia, S.; Li, S.; Liu, Y.; Qin, W.; Yan, H*. Enantioselective Control of Both Helical and Axial Stereogenic Elements though an Organocatalytic Approach. Angew. Chem. Int. Ed. 2019, 58, 18496-18501.

4.  Peng, L.; Li, K.; Xie, C.; Li, S.; Xu, D.; Qin, W.; Yan, H*. Organocatalytic Asymmetric Annulation of ortho-Alkynylanilines: Synthesis of Axially Chiral Naphthyl-C2-indoles. Angew. Chem. Int. Ed. 2019, 58, 17199-17204.

5.  Peng, L.; Xu, D.; Yang, X.; Tang, J.; Feng, X.; Zhang, S.; Yan, H*. Organocatalytic Asymmetric One-Step Desymmetrizing Dearomatization Reaction of Indoles : Development and Bioactivity Evaluation. Angew. Chem. Int. Ed. 2019, 58, 216-220.

6.  Tan, Y.; Jia, S.; Hu, F.; Liu, Y.; Peng, L.; Li, D.; Yan, H*. Enantioselective Construction of Vicinal Diaxial Styrenes and Multiaxis System via Organocatalysis. J. Am. Chem. Soc. 2018, 140, 16893-16898.

7.  Jia, S.; Chen, Z.; Zhang, N.; Tan, Y.; Liu, Y.; Deng, J.; Yan, H*. Organocatalytic Enantioselective Construction of Axially Chiral Sulfone-Containing Styrenes. J. Am. Chem. Soc. 2018, 140, 7056-7060.

8.  Liu, Y.; Wu, X.; Li, S.; Xue, L.; Shan, C.; Zhao, Z.; Yan, H*. Organocatalytic Atroposelective Intramolecular [4+2] Cycloaddition : Synthesis of Axially Chiral Heterobiaryls. Angew. Chem. Int. Ed. 2018, 57, 6491-6495.

9.  Tan, Yu.; Luo, S.; Li, D.; Zhang, N.; Jia, S.; Liu, Y.; Qin, W.; Yan, H*. Enantioselective Synthesis of anti-syn-Trihalides and anti-syn-anti-Tetrahalides via Asymmetric β-Elimination. J. Am. Chem. Soc. 2017, 139, 6431-6436.

10.  Wu, X.; Xue, L.; Li, D.; Jia, S.; Ao, J.; Deng, J.; Yan, H*. Organocatalytic Intramolecular [4+2] Cycloaddition between In Situ Generated Vinylidene ortho-Quinone Methides and Benzofurans. Angew. Chem. Int. Ed. 2017, 56, 13722-13726.

11.  Liu, Y.; Ao, J.; Paladhi, S.; Song, C. E.; Yan, H*. Organocatalytic Asymmetric Synthesis of Chiral Dioxazinanes and Dioxazepanes with in Situ Generated Nitrones via a Tandem Reaction Pathway Using a Cooperative Cation Binding Catalyst. J. Am. Chem. Soc. 2016, 138, 16486-16492.

12.  Li, L.; Liu, Y.; Peng, Y.; Yu, L.; Wu, X.; Yan, H*. Kinetic Resolution of β-Sulfonyl Ketones through Enantioselective β-Elimination using a Cation-Binding Polyether Catalyst. Angew. Chem. Int. Ed. 2016, 55, 331-335.