代磊

常年欢迎化学或药学领域的副教授/准聘副教授/弘深青年教师/博士后（年薪30-40万元）、研究生等有志之士加入团队。

代磊，男，博士，重庆大学教授，博士生导师。2024年3月以弘深青年学者A岗加入重庆大学药学院开展独立工作。2020年9月博士毕业于中国科学院化学研究所，师从国家杰青叶松研究员，随后在新加坡国立大学进行博士后研究，合作导师为新加坡国家科学院院士、化学系主任卢一新教授。曾获得中国科学院院长奖及新加坡国立大学最佳博士生指导奖。以第一作者/通讯作者发表Science Advances，Nature Communications，ACS Central Science，Chem，Angewandte Chemie， CCS Chemistry， Advanced Science， Chemical Science，ACS Catalysis等高水平论文20余篇。

课题组网站：https://www.x-mol.com/groups/dai_lei

2024.03-至今     重庆大学药学院•创新药物研究中心，教授（硕士/博士生导师）

2020.12.–2024.02  新加坡国立大学，博士后，合作导师：Prof. Yixin Lu

2017.09–2020.09   中国科学院化学研究所，理学博士，导师：叶松研究员

2014.09–2017.06   郑州大学，药学院，硕士

2010.09–2014.06   郑州大学，药学院，学士

药物化学、有机化学

可见光驱动的有机小分子催化

不对称自由基化学

药物分子骨架的精准编辑

生物活性分子的合成以及活性评价

主持重庆大学弘深青年学者启动基金

1. Dai, L.; Guo, J.; Huang, Q.; Lu, Y.* Asymmetric multifunctionalization of alkynes via photo-irradiated organocatalysis. Science Advances, 2022, 8, eadd2574. (中科院一区Top, IF = 13.6)

2. Dai, L.; Zhou, X.; Guo, J.; Dai X.; Huang, Q and Lu, Y.* Diastereo- and atroposelective synthesis of N-arylpyrroles enabled by light-induced phosphoric acid catalysis Nature Communications, 2023, 4813. (中科院一区Top, IF = 16.6)

3. Zhou, X.; Huang, Q; Guo, J.; Dai, L.*; Lu, Y.* Molecular editing of pyrroles via a skeletal recasting strategy. ACS Central Science, 2023, 1758-1767. (中科院一区Top, IF = 18.2)

4. Zhou, X.^§; Huang, Q^§; Guo, J.; Dai, L.*; Lu, Y.* Enantioselective De Novo Synthesis of a,a-Diarylketones from Alkynes. Angew. Chem. Int. Ed., 2023, e202310078. (中科院一区Top, IF = 16.6)

5. Dai, L.; Xia, Z.H.; Gao, Y.Y.; Gao, Z.H.* and Ye, S.*, Visible-Light-Driven N-Heterocyclic Carbene Catalyzed γ- and e-Alkylation with Alkyl Radicals.  Angew. Chem. Int. Ed., 2019, 58, 18124-18130. (Reviewed by Nat. Chem.) (中科院一区Top, IF = 16.6)

6. Dai, L and Lu, Y.* Atroposelective remote meta-C-H arylation of 2-arylanilines. Chem, 2023, 1347-1349. (中科院一区Top, IF = 23.5)

7. Dai, X.; Zhang, F.; Dai, L.*; Lu, Y.* Asymmetric Dearomatization of Electron-Deficient Heteroarenes by a Phosphine-Catalyzed [3+2] Annulation with Vinylcyclopropanes. CCS Chemistry, 2023, 5, 2023–2032. (中科院一区Top, IF = 11.2)

8. Dai, L.; Sun, Y.-L.; Guo, J.; Zhou, X.; Huang, Q. and Lu, Y.* Atroposelective Synthesis of 3-Aryl-indoles through a One-pot 2,3-Difunctionalization of Simple Indoles. CCS Chemistry, 2024, DOI: 10.31635/ccschem.023.202303434 (中科院一区Top, IF = 11.2)

9. Zhou, X.^§; Huang, Q^§; Guo, J.; Dai, L.*; Lu, Y.* Catalytic Asymmetric Construction of α,α-DiarylAldehydes via Oxo hydroarylation of Terminal Alkynes. Advanced Science, 2024, Accepted. (中科院一区Top, IF = 15.1) 

10. Dai, L.; Zhou, X.; Guo, J.; Huang, Q. and Lu, Y.* Copper-catalyzed atroposelective synthesis of C–O axially chiral compounds enabled by chiral 1,8-naphthyridine based ligands. Chemical Science, 2024, DOI: 10.1039/d4sc01074d. (中科院一区Top, IF = 8.4)

11. Dai, L. and Ye, S.*, NHC-catalyzed ε-umpolung via p-quinodimethanes and its nucleophilic addition to ketones. ACS Catalysis, 2020, 10, 994-998. (中科院一区Top, IF = 12.9)

12. Dai, L.; Qiu, Y.; Xu, Y.Y. and Ye, S.*, Biomass transformation of cellulose via N-heterocyclic carbene-catalyzed umpolung of 5-(chloromethyl) furfural. Cell Reports Physical Science, 2020, 1, 100071. (Cell子刊, IF = 8.9)

13. Guo, J.; Shen, Z.-A.; Zhou, X.; Dai, L.*; Lu, Y.* Light-induced phosphine-catalyzed asymmetric functionalization of benzylic C-H bonds. Science China Chemistry, 2023, 66, 127–132. (中科院一区, IF = 9.6)

14. Dai, L.; Zhang, Z.-F. and Chen, X.-Y.^*, Reduction of unactivated alkyl chlorides enabled by light-induced single electron transfer Science China Chemistry, 2024 67, 471-481. (中科院一区, IF = 9.6)

15. Dai, L. and Ye, S.*, Recent advances in N-heterocyclic carbene-catalyzed radical reactions. Chinese Chemical Letters, 2021, 32, 660-667. （2023年Chinese Chemical Letters优秀论文奖）(中科院一区, IF = 9.1)

16. Dai, L. and Ye, S.*, Photo/N-heterocyclic carbene co-catalyzed ring opening and γ-alkylation of cyclopropane enal. Organic Letters, 2020, 22, 986-990. (中科院一区Top, IF = 5.2)

17. Dai, L.; Xu, Y.Y.; Xia, Z.H. and Ye, S.*, γ-Difluoroalkylation: Synthesis of γ-difluoroalkyl-α, β-unsaturated esters via photoredox NHC-catalyzed radical reaction. Organic Letters, 2020, 22, 8173-8177. (中科院一区Top, IF = 5.2)