
学习工作经历
2016.7-至今, 重庆大学, 药学院, 讲师,副教授
2024.08-2024.11 意大利帕尔玛大学 访问学者
2014.10-2016.5, Allecra Therapeutics, 研发部, 研发顾问(中国)
2014.5-2014.9, 意大利国家科学研究院有机合成与光化学研究中心(CNR-ISOF), 研究助理
2010.11–2014.4, 博士, 意大利博洛尼亚大学化学学院, 导师: Panunzio Mauro
2007.9 –2010.6, 硕士, 重庆大学化学化工学院, 导师: 夏之宁,肖尚友
2003.9 –2007.7, 学士, 兰州大学药学院, 导师: 赵全义
研究领域
不对称合成及药物合成工艺研究
药物化学(β-内酰胺类抗生素新药发现及工艺研究)
项目成果
国家自然科学基金面上项目 (53万)
重庆市重点产业共性关键技术创新专项重点研发项目(200万)
国家自然科学基金青年项目(22.5万)
重庆大学科研启动基金(20万)
法国Allecra Therapeutic公司科技合作项目(40万)
中国人民解放军陆军特色医学中心科技合作项目(30万元)
代表性文章
1. "Catalytic asymmetric functionalization and dearomatization of thiophenes" Zhengxing Zhao, Yingxin. Li, Shiqi. Jia, Lei. Peng, Zian. Zhang, Fengdi. Wu, Pengfei. Wang, Wenling. Qin*, Yu. Lan*, Hailong. Yan* Chem. Sci., 2024, 15, 14295-14303.
2. "Enantioselective Catalytic Synthesis of Inherently Chiral Calixarenes"Wenling Qin*, Gianpiero Cera* Chem. Rec. 2025, 25, e202400237.
5. "Organocatalytic Asymmetric Construction of Tetrasubstituted Carbon Stereocenters Bearing Three Heteroatoms via Intramolecular Cyclization of Vinylidene ortho-Quinone Methide with Imidates" Yuhong. Tian, Fengdi. Wu, Shiqi. Jia, Xiangnan. Gong, Hui. Mao, Pengfei. Wang*, Wenling. Qin*, Hailong. Yan Org. Lett. 2022, 24, 5073−5077.
6. "Chiral Naphthyl-C2-Indole as Scaffold for Phosphine Organocatalysis: Application in Asymmetric Formal [4 + 2] Cycloaddition Reactions" Tingting He, Lei Peng, Shan Li, Fangli Hu, Chuandong Xie, Shengli Huang, Shiqi Jia, Wenling Qin*, Hailong Yan* Org. Lett. 2020, 22, 17, 6966-6971.
7. "N-Iodosuccinimide-Mediated Dimerization of 2-Alkynylnaphthols: A Highly Diastereoselective Construction of Bridged Polycyclic Compounds via Vinylidene ortho-Quinone Methide Intermediate" Yu Tan, Zhengxing Zhao, Zhili Chen, Shengli Huang, Shiqi Jia, Lei Peng, Da Xu, Wenling Qin*, Hailong Yan*. Org. Lett. 2020, 2020, 22, 11, 4461–4466.
8. "Antibacterial Agents Targeting the Bacterial Cell Wall" Shan Li, Wenling Qin *, Mauro Panunzio, Stefano Biondi * Curr. Med. Chem. 2020, 27, 1-24.
9. "Organocatalytic Enantioselective γ-Elimination: Applications in the Preparation of Chiral Peroxides and Epoxides" Fangli Hu, Zhili Chen, Yu Tan, Da Xu, Shengli Huang, Shiqi Jia, Xiangnan Gong, Wenling Qin* Hailong Yan* Org. Lett. 2020, 22, 5, 1934-1940.
10. "Organocatalytic Enantioselective Selenosulfonylation of a C-C Double Bond to Form Two Stereogenic Centers in an Aqueou Medium" Zhili. Chen, Fangli. Hu, Shengli. Huang, Zhengxing. Zhao, Hui. Mao* and Wenling. Qin* J. Org. Chem. 2019, 84, 8100−8111.
11. "Metal-free difunctionalization of alkynes to access tetrasubstituted olefins through spontaneous selenosulfonylation of vinylidene ortho-quinone methide (VQM)" Shengli. Huang, Zhili. Chen, Hui. Mao, Fangli. Hu, Dongmei. Li, Yu Tan, Fengqing. Yang, Wenling. Qin* Org. Biomol. Chem. 2019, 17, 1121–1129.
12. "Direct Preparation of Indole Hemiaminals through Organocatalytic Nucleophilic Addition of Indole to Aldehydes" Nan. Zhang, Yige. Li, Zhili. Chen, Wenling. Qin* Synthesis 2018, 50, 4063-4070.
13. "K2S2O8 Activated Friedel-Crafts Type Alkylation of Indoles with α-Amido Sulfones" Xiaoyan. Wu, Lu. Xue, Shilong. Luo, Shiqi. Jia, Jun. Ao, Wenling. Qin* Synthesis, 2017, 49, 5017-5024.
14. "α-Alkyl-α-aryl (Trimethyltin) Nitriles: Versatile Nucleophilic Intermediates in Aldol-Like Reactions" Wenling Qin, Sha Long, Alessandro Bongini, and Mauro Panunzio Eur. J. Org. Chem. 2015, 3495-3505.
15. "β-Lactam Antibiotics Renaissance" Wenling Qin; Sha Long, Mauro Panunzio, Stefano Biondi Antibiotics, 2014, 3 (2):193-215.
16. “一种制备含腈基γ-醇化合物的方法”(发明专利, 第一发明人,CN109824542A),已授权。