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薛伟伟职称：副教授/硕导 学历：博士 邮箱：xueww@cqu.edu.cn 电话： |
- 个人/团队介绍
- 学习工作经历
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2016/9 – 至今 重庆大学药学院·创新药物研究中心 副教授/硕士生导师
2015/11 – 2016/8重庆大学药学院·创新药物研究中心 讲师/硕士生导师
2014/7 – 2015/10 重庆大学创新药物研究中心 讲师
2009/9 – 2014/6 兰州大学化学化工学院 化学信息学 博士（导师：姚小军教授）
2005/9 – 2009/6 兰州大学化学化工学院 化学（基础理论班）学士
- 研究领域
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1. 药物-靶标识别和相互作用机理
2. 基于结构的活性分子设计与筛选
3. 蛋白-蛋白相互作用和功能蛋白质设计
- 项目成果
- 代表性文章
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25. Qingxia Yang, Yunxia Wang, Song Zhang, Jing Tang, Fengcheng Li, Jiayi Yin, Yi Li, Jianbo Fu, Bo Li, Yongchao Luo, Weiwei Xue*, Feng Zhu*, Biomarker discovery for immunotherapy of pituitary adenomas: Enhanced robustness and prediction ability by modern computational tools. Int. J. Mol. Sci. 2019, 20(1): doi:10.3390/ijms20010151.
24. Weiwei Xue*, Tingting Fu, Guoxun Zheng, Gao Tu, Yang Zhang, Fengyuan Yang, Lin Tao, Lixia Yao, Feng Zhu*. Recent advances and challenges of the drugs acting on monoamine transporters. Curr. Med. Chem. 2018, [PMID: 30306851].
23. Guoxun Zheng, Fengyuan Yang, Tingting Fu, Gao Tu, Yuzong Chen, Xiaojun Yao, Weiwei Xue*, Feng Zhu*. Computational characterization of the selective inhibition of human norepinephrine and serotonin transporters by escitalopram scaffold. Phys. Chem. Chem. Phys. 2018, 20(46): 29513-29527.
22. Jing Tang, Yang Zhang, Jianbo Fu, Yunxia Wang, Yi Li, Qingxia Yang, Lixia Yao, Weiwei Xue*, Feng Zhu*. Computational advances in the label-free quantification of cancer proteomics data. Curr. Pharm. Des. 2018, [PMID: 30387388].
21. Gao Tu, Tingting Fu, Fengyuan Yang, Lixia Yao, Weiwei Xue*, Feng Zhu*. Prediction of GluN2B-CT1290-1310/DAPK1 interaction by protein-peptide docking and molecular dynamics simulation. Molecules. 2018, 23(11), pii: E3018.
20. Fengyuan Yang, Guoxun Zheng, Tingting Fu, Xiaofeng Li, Gao Tu, Yinghong Li, Xiaojun Yao, Weiwei Xue*, Feng Zhu*. Prediction of the binding mode and resistance profile for a dual-target pyrrolyl diketo acid scaffold against HIV-1 integrase and reverse-transcriptase-associated ribonuclease H. Phys. Chem. Chem. Phys. 2018, 20(37): 23873-23884.
19. Tingting Fu, Guoxun Zheng, Fengyuan Yang, Yuzong Chen, Xiaojun Yao, Xiaofeng Li, Weiwei Xue*, Feng Zhu*. Exploring the binding mechanism of metabotropic glutamate receptor 5 negative allosteric modulators in clinical trials by molecular dynamics simulations. ACS Chem. Neurosci. 2018, 9(6): 1492-1502.
18. Weiwei Xue, Fengyuan Yang, Panpa...
