张传瑞

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张传瑞

职称:研究员/博导

学历:博士

邮箱:crzhang@cqu.edu.cn

电话:18302335377

个人/团队介绍
学习工作经历

2016.07-至今 重庆大学药学院创新药物研究中心,重庆大学百人计划特聘研究员(博士生导师)

2012.01-2015.12 博士后,密歇根州立大学,功能性食品化学,导师Muraleedharan Nair教授

2011.01-2012.01 博士后,亚利桑那大学,植物内生菌天然药物化学,导师Leslie Gunatilaka教授

2010.10-2011.01 副研究员,中国科学院上海药物研究所,天然药物化学

2008.07-2010.10助理研究员,中国科学院上海药物研究所,天然药物化学

2003.09-2008.07 药物化学博士,中国科学院上海药物研究所,师从著名天然药物化学家岳建民研究员

1999.09-2003.07 理学学士,北京师范大学,化学学院应用化学专业


研究领域

1.以活性筛选为导向从药用植物中发现具有重要生物活性的小分子化合物,以期发现新药先导化合物进而研发新药;

2.以活性筛选为导向从药食两用植物或功能性食品中发现活性物质,以期阐述他们的药用或者功能性作用机制进而开发保健品;

3.利用现代科学的理论和手段阐述传统中药的作用机制实现中药现代化。


项目成果
代表性文章

1.Chuan-Rui Zhang, Wajid Khan, Jehan Bakht, Muraleedharan G Nair. New antiinflammatory sucrose esters in the natural sticky coating of tomatillo (Physalis philadelphica), an important culinary fruitFood Chemistry 2016, 196, 726-732.

2.Hua Zhang*, Chuan-Rui Zhang*, Ying-Shan Han, Mark A. Wainberg, Jian-Min Yue. New Securinega alkaloids with anti-HIV activity from Flueggea virosaRSC Advances 2015, 5, 107045-107053. (*Equal contribution)

3.Chuan-Rui Zhang, Amila A. Dissanayake, Muraleedharan G. Nair. Functional food property of honey locust (Gleditsia triacanthos) flowers. Journal of Functional Foods 2015, 18, 266-274.

4.Chuan-Rui Zhang, Ettannil Jayashree, Paramasivam Suresh Kumar, Muraleedharan G. Nair. Antioxidant and antiinflammatory compounds in nutmeg (Myristica fragrans) pericarpNatural Product Communications 2015, 10, 1399-1402.

5.Chuan-Rui Zhang, Amila A. Dissanayake, Kudret Kevsero?lu, Muraleedharan G. Nair. Evaluation of coriander spice as a functional food by using in vitro bioassays. Food Chemistry 2015, 167, 24-29.

6.Chuan-Rui Zhang, Saleh A. Aldosari, Polana S. P. V. Vidyasagar, Karun M. Nair, Muraleedharan G. Nair.Antioxidant and anti-inflammatory assays confirm bioactive compounds in ajwa date fruit. Journal of Agricultural and Food Chemistry 2013, 61, 5834-5840.

7.Chuan-Rui Zhang, Robert E. Schutzki, Muraleedharan G. Nair. Antioxidant and anti-inflammatory compounds in the popular landscape plant Berberis thunbergii var. atropurpureaNatural Product Communications 2013, 8(2), 165-168.

8.Chuan-Rui Zhang, Hong-Bing Liu, Shi-Hui Dong, Yan Wu, Jian-Min Yue. Alkaloids from the twigs and leaves ofDaphniphyllum macropodumHelvetica Chimica Acta 2013, 96, 499-504.

9.Chuan-Rui Zhang, Cheng-Qi Fan, Shi-Hui Dong, Hong-Bing Liu, Wen-Bin Zhou, Yan Wu, and Jian-Min Yue. Angustimine and angustifolimine, two new alkaloids from Daphniphyllum angustifoliumOrganic Letters 2011, 13(9), 2440-2443.

10.Chuan-Rui Zhang, Yan Wu, and Jian-Min Yue. Polyoxygenated sec...