Wenling Qin

Asymmetric catalysis and pharmaceutical process development

Discovery of novel antibiotics

1.  National Natural Science Foundation of China

2.  Special Key Research and Development Projects of Common Key Technology Innovation for Key Industries in Chongqing

3.  Corporate sponsorship from Industries

1.  "Chiral Naphthyl-C2-Indole as Scaffold for Phosphine Organocatalysis: Application in Asymmetric Formal [4 + 2] Cycloaddition Reactions" Tingting He, Lei Peng, Shan Li, Fangli Hu, Chuandong Xie, Shengli Huang, Shiqi Jia, Wenling Qin*, Hailong Yan* Org. Lett. 2020, 22, 17, 6966-6971.

2.  "N-Iodosuccinimide-Mediated Dimerization of 2-Alkynylnaphthols: A Highly Diastereoselective Construction of Bridged Polycyclic Compounds via Vinylidene ortho-Quinone Methide Intermediate" Yu Tan, Zhengxing Zhao, Zhili Chen, Shengli Huang, Shiqi Jia, Lei Peng, Da Xu, Wenling Qin*, Hailong Yan*. Org. Lett. 2020, 2020, 22, 11, 4461–4466.

3.  "Antibacterial Agents Targeting the Bacterial Cell Wall" Shan Li, Wenling Qin *, Mauro Panunzio, Stefano Biondi * Curr. Med. Chem. 2020, 27, 1-24.

4.  "Organocatalytic Enantioselective γ-Elimination: Applications in the Preparation of Chiral Peroxides and Epoxides" Fangli Hu, Zhili Chen, Yu Tan, Da Xu, Shengli Huang, Shiqi Jia, Xiangnan Gong, Wenling Qin* Hailong Yan* Org. Lett. 2020, 22, 5, 1934-1940.

5.  "Organocatalytic Enantioselective Selenosulfonylation of a C-C Double Bond to Form Two Stereogenic Centers in an Aqueou Medium" Zhili. Chen, Fangli. Hu, Shengli. Huang, Zhengxing. Zhao, Hui. Mao* and Wenling. Qin* J. Org. Chem. 2019, 84, 8100−8111.

6.  "Metal-free difunctionalization of alkynes to access tetrasubstituted olefins through spontaneous selenosulfonylation of vinylidene ortho-quinone methide (VQM)" Shengli. Huang, Zhili. Chen, Hui. Mao, Fangli. Hu, Dongmei. Li, Yu Tan, Fengqing. Yang, Wenling. Qin* Org. Biomol. Chem. 2019, 17, 1121–1129.

7.  "Direct Preparation of Indole Hemiaminals through Organocatalytic Nucleophilic Addition of Indole to Aldehydes" Nan. Zhang, Yige. Li, Zhili. Chen, Wenling. Qin* Synthesis 2018, 50, 4063-4070.

8.  "K₂S₂O₈ Activated Friedel-Crafts Type Alkylation of Indoles with α-Amido Sulfones" Xiaoyan. Wu, Lu. Xue, Shilong. Luo, Shiqi. Jia, Jun. Ao, Wenling. Qin* Synthesis, 2017, 49, 5017-5024.

9.  "α-Alkyl-α-aryl (Trimethyltin) Nitriles: Versatile Nucleophilic Intermediates in Aldol-Like Reactions" Wenling Qin, Sha Long, Alessandro Bongini, and Mauro Panunzio Eur. J. Org. Chem. 2015, 3495-3505.

10.  "β-Lactam Antibiotics Renaissance" Wenling Qin; Sha Long, Mauro Panunzio, Stefano Biondi  Antibiotics, 2014, 3 (2):193-215.