Wu Wen

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2006.09-2010.07, Sichuan University, majored in pharmacy, B.S.

2010.09-2012.07, Wuhuan University, majored in pharmacy, M.S. (Supervisor: Hu xian ming)

2012.10-2016.02, University of Lorraine (France), majored in pharmacy, Ph.D. (Supervisor: Philippe Maincent)

2016.07-present, Chongqing University, Lecturer

Development of novel drug delivery systems

Development and applications of biomaterials

2016,            First prize for thesis in university of Lorraine, France

2012-2016,  China Scholarship Council Fellowship

(*: corresponding author; †: equal contribution)

1.  Wu W.*†,  Chen M.†; Luo T.R.; Fan Y.;, Zhang J.Q.; Zhang Y.; Zhang Q.Y.; Sapin-Minet A.; Gaucher C.; Xia X.F.* ROS and GSHresponsive S-nitrosoglutathione functionalized polymeric nanoparticles to overcome multidrug resistance in cancer, Acta Biomaterialia (2020), 259-271.

2.  Fan Y.; Chen M.; Zhang JQ; Maincent P.; Xia XF*; Wu W.*, Updated progress of nanocarrier-based intranasal drug delivery systems for treatment of brain diseases, Critical Reviews™ in Therapeutic Drug Carrier Systems, 35(2018) 433–467.

3.  Fan Y.; Wu W.*; Lei Y.; Gaucher C.; Pei SC.; Zhang J.; Xia X.*, Edaravone-loaded alginate-based nanocomposite hydrogel acclerated chronic wound healing in diabetic mice, marine drugs, 17(2019) 285.

4.  Wu, W.; Perrin-Sarrado, C.; Ming, H.; Lartaud, I.; Maincent, P.; Hu, X.M.; Sapin-Minet, A. and Gaucher C. Polymer nanocomposites enhance S-nitrosoglutathione intestinal absorption and promote the formation of releasable nitric oxide stores in rat aorta, Nanomedicine: NBM, 12 (2016) 1795–1803.

5.  Wu W.; Gaucher C.; Diab R.; Fries I.; Xiao Y.L.; Hu X.M.; Maincent P. and Sapin-Minet A. Time lasting S-nitrosoglutathione polymeric nanoparticles delay cellular protein S-nitrosation, Eur. J. Pharm. Biopharm. 89 (2015) 1-8.

6.  Wu, W.; Gaucher, C.; Fries-Raeth, I; Xiao, Y.L.; Hu, X.M.; Maincent, P. and Sapin-Minet, A. Polymeric nanocomposite particles of s-nitrosoglutathione：a suitable formulation for protection and sustained oral delivery, Int. J. Pharma. 495(2015) 354-361.

7.  Hong Li, Yuchen Hu, Qi Pu, Tong He, Qianyu Zhang, Wen Wu, Xuefeng Xia *, Jinqiang Zhang* Novel Stapling by Lysine Tethering Provides Stable and Low Hemolytic Cationic Antimicrobial Peptides, J. Med. Chem. 63 (2020) 4081-4089.

8.  Zhang Q.Y.; Wu W.; Zhang J.Q.; Xia X.F., Eradication of Helicobacter pylori: the power of nanosized formulations，Nanomedicine 15(2020):527-542. doi: 10.2217/nnm-2019-0329.

9.  Zhang Q.Y.; Wu W.; Zhang J.Q.; Xia X.F., Antimicrobial lipids in nano-carriers for antibacterial delivery , Journal of Drug Targeting, (2019) DOI: 10.1080/1061186X.2019.1681434.

10.  Dai C.; Ma J.; Li M.; Wu W.; Xia XF.; Zhang JQ., Diversity-oriented submonomer synthesis of azapeptides mediated by the mitsunobu reaction, Organic Chemistry Frontiers, 6 (2019) 2529.

11.  Belcastro, E; Wu, W.; Fries-Raeth, I; Corti, A; Pompella, A; Leroy, P; Lartaud, I; Gaucher, C. Oxidative stress enhances and modulates protein S-nitrosation in smooth muscle cells exposed to S-nitrosoglutathione, Nitric Oxide 69(2017) 10-21.

12.  Ramia Safar, Rémi Houlgatte, Alain Le Faou, Carole Ronzani, Wen Wu, Luc Ferrari, Hélène Dubois-Pot-Schneider, Bertrand H. Rihn & Olivier Joubert. Encapsulation of  S-nitrosoglutathione: a transcriptomic validation, Drug Development and Industrial Pharmacy, 45(2019), 423-429.