Yi Xia

1998.09-2002.06, Wuhan University, majored in chemistry, B.S.

2002.09-2007.06, Wuhan University, majored in bioorganic chemistry, Ph. D.

2007.09-2007.11, Université de la Méditerranée, Visiting scholar.                 

2008.01-2010.12, CINaM, CNRS UMR 7325, France, Post-doctor.

2011.01-2012.08, CINaM, CNRS UMR 7325, France, Research associate.

2012.09-2014.08, Vancouver Prostate Centre, Canada, Post-doctor.

2014.09-now, Chongqing University, Associate Professor.

Development of drug candidates for targeted anticancer therapy

Anticancer mechanism of action

Supramolecular self-assembling nanodrugs

Awards

1. 2016: Outstanding Reviewer for New Journal of Chemistry.

2. 2017: Supervisor Award for Outstanding Undergraduate Dissertation of Chongqing University.

3. 2019 National Competition of Microlecture (Pharmaceutical Sciences), First Prize.

4. 2019 National Competition of Teaching Skills (Pharmaceutical Sciences), Second Prize.

Grants and Funding

National Natural Science Foundation of China

Natural Science Foundation Project of CQ CSTC

“Xu Guangqi” Sino-French Scientific Cooperation Project

“Cai Yuanpei” Sino-French Scientific Cooperation Project

Jeunes Talents France-Chine Program (JTFC)

Fundamental Research Funds for the Central Universities

1. Yanhua Zhang#, Xi Liu#, Yun Lin, Baoping Lian, Wenjun Lan, Juan L. Iovanna, Xiaoxuan Liu*, Ling Peng, Yi Xia*. “Novel Triazole Nucleoside Analogues Promotes Anticancer Activity via Both Apoptosis and Autophagy.” Chem. Commun., 2020, 56, 10014-10017.

2. Yanhua Zhang#, Yun Lin#, Qianqian Hou, Xi Liu, Sabrina Pricl, Ling Peng, Yi Xia*. “Novel Aryltriazole Acyclic C-Azanucleosides as Anticancer Candidates.” Org. Biomol. Chem. 2020, 18, 9689-9699.

3. Zhengwei Zhou^#, Biyao Luo^#, Xi Liu^#, Mimi Chen, Wenjun Lan, Juan L. Iovanna, Ling Peng*, Yi Xia*. “Flavonoid–alkylphospholipid conjugates elicit dual inhibition of cancer cell growth and lipid accumulation.” Chem. Commun., 2019, 55, 8919-8922. (Inside cover paper)

4. Patricia Santofimia-Castaño^#, Yi Xia^#, Wenjun Lan^#, Zhengwei Zhou, Can Huang, Ling Peng, Philippe Soubeyran, Adrián Velázquez-Campoy, Olga Abián, Bruno Rizzuti, José L Neira*, Juan Iovanna*. “Ligand-based design of a potent inhibitor of the intrinsically disordered protein NUPR1 with anticancer activity via programmed necrosis.” J. Clin. Invest., 2019, 129, 2500-2513. (co-first author)

5. Zhengwei Zhou^#, Mei Cong^#, Mengyao Li, Aura Tintaru, Jia Li, Jianhua Yao, Yi Xia*, Ling Peng*, “Negative dendritic effect on enzymatic hydrolysis of dendrimer conjugates”. Chem. Commun., 2018, 54, 5956-5959. (Inside cover paper)