方华权Title:教授,硕/博导 E-mail Address:fanghq@cqu.edu.cn Tel.: |
常年欢迎化学或药学领域的副教授/准聘副教授/弘深青年教师/博士后(年薪30-40万元)、研究生等青年才俊的加盟!欢迎联合培养生、本科生以及科研助理入组交流学习!
方华权,重庆大学教授,博士生导师。2024年10月以弘深青年学者A岗加入重庆大学药学院开展独立工作。2018年博士毕业于中国科学院上海有机化学研究所,师从黄正研究员,主要从事新型钌络合物的开发及其应用。2018—2020年获德国“亚历山大・冯・洪堡基金会(Alexander von Humboldt-Stiftung)”资助在柏林工业大学开展第一站博士后研究,合作导师为Martin Oestreich教授,主要从事硼路易斯酸催化的有机转化。2021年于上海睿智化学担任有机合成高级研究员。2021—2024年,在英国布里斯托大学开展第二站博士后研究,合作导师为Varinder K. Aggarwal教授,主要从事过渡金属催化的不对称催化转化。至今,以第一作者(含共同)发表学术论文12篇,包括J. Am. Chem. Soc.(1篇),Angew. Chem. Int. Ed.(3篇),Chem. Sci.(1篇),Org. Lett.(2篇)和 Org. Chem. Front. (1篇)等;授权国内专利1项;撰写英文专著章节2章。
2024.10—至今 重庆大学药学院•创新药物研究中心,教授(硕士/博士生导师)
2021.10—2024.09 布里斯托大学,博士后,合作导师:Prof. Varinder K. Aggarwal
2021.03—2021.08 上海睿智化学,高级合成研究员
2019.01—2020.12 柏林工业大学,博士后,合作导师: Prof. Martin Oestreich
2013.09—2018.06 中国科学院上海有机化学研究所,理学博士,导师:黄正 研究员
2009.09—2013.06 北京师范大学,学士
路易斯酸催化,过渡金属催化,不对称催化,手性药物中间体开发
主持重庆大学弘深青年学者启动基金
1. H. Fang, N. Manoj, M. V. Popescu, A. Noble, R. S. Paton,* and V. K. Aggarwal,* Platinum-Catalyzed Regio- and Enantioselective Diboration of Unactivated Alkenes with (pin)B−B(dan), Angew. Chem. Int. Ed. 2024, 63, e202413504.
2. H. Fang, K. Xie, S. Kemper, and M. Oestreich,* Consecutive β,β’-Selective C(sp3)–H Silylation of Tertiary Amines with Dihydrosilanes Catalyzed by B(C6F5)3, Angew. Chem. Int. Ed., 2021, 60, 8542–8546.
3. H. Fang and M. Oestreich,* Reductive Deamination with Hydrosilanes Catalyzed by B(C6F5)3, Angew. Chem. Int. Ed., 2020, 59, 11394–11398.
4. H. Fang, W. Hou, G. Liu, and Z. Huang,* Ruthenium-Catalyzed Site-Selective Intramolecular Silylation of Primary C−H Bonds for Synthesis of Sila-Heterocycles, J. Am. Chem. Soc., 2017, 139, 11601–11609.
5. H. Fang and M. Oestreich,* Defunctionalisation Catalysed by Boron Lewis Acids, Chem. Sci., 2020, 11, 12604–12615.
6. H. Fang,† G. Wang,† and M. Oestreich,* Mild reductive rearrangement of oximes and oxime ethers to secondary amines with hydrosilanes catalyzed by B(C6F5)3, Org. Chem. Front., 2021, 8, 3280–3285. († equal contribution)
7. H. Fang,† Q. He,† G. Liu, and Z. Huang,* Ruthenium-Catalyzed Hydrodefluorination with Silane as the Directing and Reducing Group, Org. Lett., 2020, 22, 9298–9302.
8. H. Fang, L. Guo, Y. Zhang, W. Yao, and Z. Huang,* A Pincer Ruthenium Complex for Regioselective C−H Silylation of Heteroarenes, Org. Lett., 2016, 18, 5624–5627.
9. H. Fang, Q. He, G. Liu, and Z. Huang,* Pincer Ruthenium-Catalyzed Intramolecular Silylation of C(sp2)−H Bonds, Synlett 2017, 28, 2468–2472.
10. W. Chen,† H. Fang,† K. Xie, and M. Oestreich,* The Cyclohexa-2,5-dienyl Group as a Placeholder for Hydrogen: Organocatalytic Michael Addition of an Acetaldehyde Surrogate, Chem. Eur. J., 2020, 26, 15126–15129.
11. W. Yao,† H. Fang,† Q. He, D. Peng, G. Liu, Z. Huang,* A BEt3-Base Catalyst for Amide Reduction with Silane, J. Org. Chem., 2019, 84, 6084–6093.
12. Y. Zhang,† H. Fang,† W. Yao, X. Leng, and Z. Huang,* Synthesis of Pincer Hydrido Ruthenium Olefin Complexes for Catalytic Alkane Dehydrogenation, Organometallics 2016, 35, 181–188.
13. H. Fang, G. Liu, and Z. Huang,* Pincer Iridium and Ruthenium Complexes for Alkane Dehydrogenation, in The Chemistry of Pincer Compounds, D. Morales-Morales, Eds., Elsevier, 2018, pp. 383–399.
14. H. Fang, G. Liu, and Z. Huang,* Dehydrogenation of Alkanes Using Molecular Catalysts in Alkane Functionalization, A. J. L. Pombeiro, M. F. C. Guedes da Silva, Eds., Wiley, 2018, pp. 467–483.