刘易东

刘易东博士，弘深青年学者, 硕/博士生导师。从事不对称有机小分子催化以及活性手性分子合成相关领域的研究。曾获2020年度重庆市优秀博士学位论文，首届川渝科技学术大会优秀论文一等奖等。在J. Am. Chem. Soc.，Angew. Chem. Int. Ed.，Org. Lett.等国际主流志上发表多篇论文。

2021/07-至今           弘深青年学者，重庆大学药学院•创新药物研究中心

2019/08-2021/06      博士后，丹麦奥胡斯大学  合作导师：Prof. Karl Anker Jørgensen

2013/09-2019/07      博士，化学工程与技术，重庆大学  导师：闫海龙教授

2008/09-2012/07      学士，药物制剂，中国药科大学

不对称有机小分子催化，具有活性手性分子的设计与合成，药物中间体开发

1.Yidong Liu, Joseph A. Izzo, David McLeod, Sebastijan Ričko, Esben B. Svenningsen, Thomas B. Poulsen, Karl Anker Jørgensen* Organocatalytic Asymmetric Multicomponent Cascade Reaction for the Synthesis of Contiguously Substituted Tetrahydronaphthols, J. Am. Chem. Soc. 2021, 143, 8208–8220.

2.Yidong Liu, Song Liu, Dongmei Li, Nan Zhang, Lei Peng, Jun Ao, Choong Eui Song, Yu Lan,* Hailong Yan* Kinetic Resolution of Allylic Alcohol with Chiral BINOL-based Alkoxides: A Combination of Experimental and Theoretical Studies, J. Am. Chem. Soc. 2019, 141, 1150–1159.

3.Yidong Liu, Jun Ao, Sushovan Paladhi, Choong Eui Song,* Hailong Yan* Organocatalytic Asymmetric Synthesis of Chiral Dioxazinanes and Dioxazepanes with in Situ Generated Nitrones via a Tandem Reaction Pathway Using a Cooperative Cation Binding Catalyst, J. Am. Chem. Soc. 2016, 138, 16486–16492.

4.Yidong Liu, Xiaoyan Wu, Shan Li, Lu Xue, Chunhui Shan, Zhengxing Zhao, Hailong Yan* Organocatalytic Atroposelective Intramolecular [4+2] Cycloaddition: Synthesis of Axially Chiral Heterobiaryls, Angew. Chem. Int. Ed. 2018, 57, 6491–6495.

5.Anqi Huang, Lili Zhang, Dongmei Li, Yidong Liu,* Hailong Yan,* Wenjun Li* Asymmetric One-pot Construction of Three Stereogenic Elements: Chiral Carbon Center, Stereoisomeric Alkenes and Chirality of Axial Styrenes, Org. Lett. 2019, 21, 95–99.